Welcome to the website for the UK PSC Genetics Study.
The purpose of this site is to act as a go-to for participants and clinical staff involved in the UK PSC Study. We aim to publish or link to any papers arising from the study as well as producing quarterly newsletters with updates on the status of the study. To receive our quarterly newsletter and updates on any research published as a result of the UK PSC Genetics Study please click here
For the latest Autumn 2012 edition of the PSC Genetics Study Newsletter click here.
The aim of this UK collaborative study is to collect DNA and clinical details from 1000-2000 patients with primary sclerosing cholangitis (PSC) to perform clinical, epidemiological and genetic studies.
The UK PSC Consortium (UK PSC) comprises lead project investigators and multiple local collaborators who are active in recruiting PSC cases and was established in 2009. The Project is funded by charitable donations managed by Dr Roger Chapman (Oxford) and by The Norwegian PSC Research Center (Dr Tom Hemming-Karlsen). Patient recruitment is co-ordinated from the Department of Medical Genetics, University of Cambridge by a research administrator, Kelly Spiess and a clinical research fellow, Dr Brijesh Srivastava.
The study has full ethical approval (MREC number 08/H0305/45) and R&D approval has been gained in most participating UK centres.
Patients with PSC are being identified from outpatient clinics in participating UK centres; from the UK and Ireland Transplant and Audit Commission and from the PSC Trust and PSC Support group.
We would like to express our gratitude to everyone who has participated in the PSC Genetics Study as well as to our collaborators and clinical colleagues who have all made major contributions to the study. We welcome your continuing support.